Endocrine Abstracts

Previous observational studies found associations between Helicobacter pylori infection and autoimmune thyroid diseases (AITDs), but the causal nature of this association is still uncertain. We investigated the causal effect of 6 crucial antibodies against H. pylori on AITDs using a bidirectional Mendelian randomization (MR). We found anti-H. pylori OMP significantly increased the risk of hyperthyroidism and Graves’ disease (GD). In addition, ou...

Objective: Some observational studies have suggested the association between thyroid function and polycystic ovary syndrome (PCOS). However, it remains to be determined whether these associations are causal or not. The aim of this study was to investigate the underlying causal association between different thyroid function status and PCOS.Methods: Bidirectional Mendelian randomization (MR) analysis was conducted to explore the impact of different thyroid...